User blog comment:Mikeylango/Game leads vs. Super heroes battle one: Master chief vs. Iron man (Movie rendition)/@comment-5422903-20130425113907/@comment-143604-20130425203504

"If Cortana was counted in the fight, as in outside of the plot, couldn't she potentially shut down Iron Man's armor?"

I doubt it. Traditionally, at least in the games, Cortana doesn't seem to wirelessly hack into anything- Chief has always had to manually take her out of his helmet and plug her into things to access tech. Either way, JARVIS would likely be able to defend against a hack well enough.