User blog comment:Appelmonkey/Undertale vs. Puella Magi Madoka Magica Mini Series, Episode 1/Sans vs. Homura Akemi/@comment-3189283-20160708145320

Lets' see shall we

Offensive

Homura has a pretty standard modern warrior loadout with various automatic weapons and pistols and her superhuman physicality should enable her to survive or dodge many of Sans' attacks (it won't make a difference in an offensive role as one hit will kill Sans anyway). Sans on the other hand has more supernatural powers such as bones & Ghaster Blasters as well as telekinesis which theoretically should allow him to stop bullets mid air or simply take the weapons right out of Homura's hands. Furthemore he also has two attacks with status ailments in Blue Mode and Karmic Retribution, with the former counteracting Homura's superhuman agility and the latter slowly damaging her over time. As for the  Chronokinesis abilities of both I would give the edge to Homura because she A) uses it far more often and B) it allows her to rewind time as well as just simply stop it which gives her an infinate number of resets if she messes up. I would give the edge here to Sans for sheer vesatility but Homura's ability to reset the timeline is too big of an advantage to overlook.

Edge: Homura Akemi

Defensive 

TBC