Isaac Clarke

Born in 2465, Isaac lived with his parents Poul Clarke, a ship designer, and Octavia Clarke, a Unitologist, in the Northeastern American seaboard sector. As a child, Isaac lived most of his life with his mother as his father left before he could even get to know him. Isaac took after his father and obtained an education in electrical and mechanical engineering, later selected to attend a prominent engineering academy. Unfortunately, he was unable to afford the tuition fees as his mother, a devoted Unitologist, spent the family funds to purchase a vested-level title in the Church of Unitology.

Despite financial difficulties, Isaac managed to graduate with high honors from a lesser college and became a systems engineer. Several years later, he signed up for the Merchant Marines division, allowing him to illustrate his abilities in original engineering solutions to his superiors. Impressed by his progress, Isaac's superiors promoted Isaac to a position closer to major shipping lines. According to Nicole in Dead Space Extraction, Isaac had apparently worked on the Ishimura in the past. Isaac previously lived with his girlfriend Nicole Brennan, but his career had began to stagnate around the same time as her assignment - and promotion - to the Ishimura two years prior to its communication blackout.

In 2508, Isaac was part of an emergency response unit attached to the USG Kellion. The crew was dispatched to the USG Ishimura, a CEC mining ship last reported to be over Aegis VII, to investigate and handle the ship's problems. After "shocking out", the Kellion tried to hail the Ishimura and establish communication with the ship's crew. Unfortunately, as the Kellion tried to land into the Ishimura's landing bay, the ship was severely damaged due to a docking procedure malfunction and was forced to crash into the landing bay, severely damaging the ship and losing its port boosters. Shortly after disembarking from the damaged Kellion and noticing that the ship seemed deserted, the party was attacked by several unidentified entities in the flight lounge, later revealed to be infected crew members now known as Necromorphs. In the aftermath of the attack, only Computer Specialist Kendra Daniels, and the team's commander, Zach Hammond survived.

Amidst the chaos, Isaac was separated from the emergency response unit and avoided his pursuers by escaping in a nearby elevator. Isaac was left with no available means of escape, as the Kellion was destroyed when Isaac attempted to repair it after returning to the docking bay. Still in touch with Kendra and Hammond via com-link and hololink, Isaac aided in the Ishimura's repair through orders involving numerous tasks across the ship. Despite being opposed at every turn by an unyielding Necromorph infestation, and later the deranged Unitologist Dr. Mercer, a C.Q.D beacon was eventually placed on an asteroid chunk undergoing ore extraction and purged from the mining hold. The signal attracted the attention of a military vessel, the USM Valor. However, the crew of the Valor was slaughtered by a Necromorph shortly thereafter when they retrieved an Ishimura escape pod which contained a Slasher, trapped and jettisoned from the ship's bridge by Hammond. With its crew dead, the Valor was left to drift out of control and subsequently sideswiped the Ishimura, violently crashing into it. A successful attempt to retrieve the Valor's singularity core nonetheless resulted in Hammond's death at the hands of an Enhanced Brute. Returning to the Ishimura, Isaac was contacted by Dr. Terrence Kyne, a scientist who planned to return the Red Marker to the colony below via the remaining shuttle. After Isaac repaired the shuttle with the Valor's singularity core and restored its navigation discs, Kyne was shot and killed by the duplicitous Kendra Daniels. She departed with the Marker, revealing herself to be a covert Earth Government agent, and that the entire conflict on Aegis VII was due to C.E.C. interference with the Marker.

Left for dead on the Ishimura, Isaac was saved by Nicole. After appearing, she compelled him to take the Marker back to Aegis VII, recalled the shuttle in the process and forced Kendra to escape in an escape pod. Once on the colony world, Isaac found the colony to be abandoned and encountered nothing but more death and gore, along with scribbled Unitologist writings that were similar to the writings on the marker. Pulling the Marker through the Necromorph-infested colony, Isaac finally succeeded in returning it to its pedestal. This resulted in a massive, blinding pulse of unknown energy that disabled the gravity tethers holding the cracked chunk of Aegis VII. However, Kendra appeared and removed the Marker from the pedestal, intending to load it into the shuttle and return to Earth.

Before leaving Isaac to his fate, Kendra insisted that he had gone insane, and forced him to watch the conclusion to the last holo-tape of Nicole that was viewed in the beginning. After professing her love for Isaac, it was revealed that Nicole committed suicide in the wake of the spreading Necromorph massacre. It seems that the Marker itself caused Isaac to hallucinate Nicole's voice and appearance during his horrifying journey through the bowels of the ill-fated Ishimura. Despondent yet determined to survive, Isaac returned to the shuttle pad in time to see a tentacle brutally kill Kendra. The ground shook as Kendra's body was savagely dismembered, and the Hive Mind towered from its confine after previously being kept at bay by the Marker. The Hive Mind viciously attacked Isaac with its tentacles but was defeated by Isaac whom destroyed its "organs".

After the engagement, Isaac piloted the shuttle just in time to escape the colony as the tectonic load crashed down onto the planet. After his narrow escape, Isaac was left alone on the shuttle to lament his experience; he reviewed the video once more on the main holo-console. In his heartbroken state, Isaac stopped the video, deactivated all holographic displays and stared disconsolately into space. A sudden, soft movement to his right caught his eye, and he turned to face a hallucination of a bloody, decaying Nicole that screamed in his face.

(From the Dead Space Wiki)