User blog comment:The Deadliest Warrior/Gru vs. Megamind/@comment-1017446-20110502024938

Gru, partially because he's voiced by Steve Carrell (why did you leave The Office D=), his disentegrator is his main killer weapon. Even though Megamind does have the invisible car, it's not particularly lethal unless he rams into Gru. I've never seen the movies but based on the trailers it seems like Gru's minions have rocket launchers and stuff. Mega's downfall is his spiked boots.